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[DOI] [PMC free article] [PubMed] [Google Scholar] Marei H, Tsai W-TK, Kee Y-Set al

Wei K, Liao X, Yang T, et al

The role of insulin and IGF-1 signaling in longevity

Conditions associated with subnormal 5-NT levels Lead poisoning Lead exposure can lead to subnormal levels of 5-NT due to direct inhibitory effects on the enzyme in serum 120,121 and red blood cells

The GPx activity was found to be positively correlated with the decrease in TNB-absorbance, a yellow-colored anion specifically associated with unreacted glutathione

A disruption of GSH homeostasis could induce oxidative stress and lead to neurodegenerative diseases, including amyotrophic lateral sclerosis, Parkinsons disease, Alzheimers disease, and dementia, with impaired motor and cognitive functions [7]