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Side effects are rare but can include mild irritation at the injection site

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Response: We remind commenters that, as stated in the code descriptor for ASCVD risk assessment, billing practitioners may choose to assess for additional domains beyond those listed above if the tool used requires additional domains. We are also not requiring the use of any specific ASCVD risk assessment tool

Decreased levels of TNF- and IL-6 indicate that NNMT inhibition not only modulates metabolism but also improves the inflammatory microenvironment, a key component in metabolic disease development and insulin resistance

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