Holder and operator GERDA Laboratories 24 rue Erlanger 75016 - PARIS
This helps healthcare providers maximize the benefits of B12 injections while reducing risks
It is also important to note that different conditions affect HbA1c in different ways: Haemolytic anaemia and acute blood loss shorten red cell lifespan and tend to lower HbA1c Iron deficiency anaemia is associated with increased HbA1c, likely due to prolonged red cell survival Haemoglobin variants (haemoglobinopathies) can cause variable or assay-dependent interference the effect depends on the specific variant and the HbA1c method used B12 or folate deficiency alters erythropoiesis and red cell indices, making HbA1c potentially unreliable in either direction Clinicians should therefore: Review the full blood count (FBC) alongside HbA1c Check serum B12 and folate when anaemia or macrocytosis (raised mean corpuscular volume, MCV) is identified Consider alternative glucose assessment methods specifically fasting plasma glucose or a 75 g OGTT for diagnostic purposes, or self-monitored blood glucose (SMBG) or fructosamine/glycated albumin for interim monitoring when HbA1c is unreliable Not sure where to start
Journal of Clinical Pharmacy and Therapeutics, 47(4), 543-556
Clemmons DR, Moses AC, McKay MJ et al (2000) The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes: evidence for in vivo biological activity
This might result in increased body mass
