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When it comes to cannabis, the results are even more mixed

Nicotine Replacement Therapy (NRT) Nicotine Replacement Therapy (NRT) is an FDA-approved method for treating nicotine dependence

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Factors that affect how long nicotine stays in your system The following factors affect how long nicotine stays in the system: Frequency and amount of nicotine use: Regular users retain nicotine and its metabolites in their system longer than those who use it occasionally

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