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PV2-S71 + PV3-N77 exhibited the highest BsNb yield of 74.9%, while PV2-S26 + PV3-S85 showed a low coupling efficiency of 52.9% compared to other BsNbs (Fig

Blood 116 , 43384348 (2010)

From a mechanistic perspective, iodine status creates a U -shaped risk curve for neurological outcomes: insufficient intake undermines hormone synthesis and cognitive capacity, while excess fosters autoimmunity and inflammatory cascades (145)