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JTCVS Open 3:128-135, 2020

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Findings indicate that CYP2C19 and CYP2D6 polymorphisms markedly affect plasma concentrations, therapeutic outcomes, and adverse-event riskwhere poor metabolizers exhibit increased efficacy but greater toxicity, while ultrarapid metabolizers show reduced therapeutic response

Toward improving crop yield and productivity, changes in physiological, biochemical, and metabolic processes of plants affected by the abiotic stresses and their response mechanisms have been studied extensively (Hasanuzzaman et al., 2017

First, in ALS, the mutant SOD1 interacts with mitochondrial membrane proteins such as Bcl-2 and VDAC1, leading to conformational changes in these proteins that expose their death domains, triggering apoptosis (116)

It is a peptide derived from a protective protein naturally found in the stomach