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16, 21 Therefore, we have undertaken extensive studies to determine the potential for BSO to enhance the anti-myeloma activity of L-PAM at clinically achievable doses using in vitro (cell lines and fresh MM explants) and in vivo MM xenografts to determine if BSO+L-PAM warrants clinical trials in MM

doi: 10.1016/j.freeradbiomed 176 JekovJurovcovVWenchichLHanskovHZemanJHnaVet al

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It means the nervous system is still recalibrating