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Li J, Xi W, Li X, Sun H, Li Y

Ermens, A

Circulating MOTS-c is detectable in humans and declines with age, but no completed human trial of administered MOTS-c has read out

This was observed in diverse population cohorts with multiple ethnic backgrounds, enhancing the generalizability of the results

Patients with evidence of vitamin B 12 deficiency and chronic gastrointestinal symptoms such as dyspepsia, recurrent peptic ulcer disease, or diarrhea may warrant evaluation for such entities as Whipple's disease (a rare bacterial infection that impairs absorption), Zollinger-Ellison syndrome (gastrinoma causing peptic ulcer and diarrhea), or Crohn's disease