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The WHO, Campaign for Tobacco Free Kids, and other advocates frequently cite research claiming that, on average, a 1% increase in the price of cigarettes leads to a 0.4% decrease in overall tobacco use in high-income countries, and 0.5% for low-income countries

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With this issuance, these ZYN nicotine pouch products which have been authorized for sale in the United States since January 2025 may now be marketed with the following risk modification claim: "Using ZYN instead of cigarettes puts you at a lower risk of mouth cancer, heart disease, lung cancer, stroke, emphysema, and chronic bronchitis." FDA authorizes 20 ZYN nicotine pouches be marketed with modified risk claim Dig deeper An order permitting the sale of a modified risk tobacco product (MRTP) refers to specific products, not an entire class of tobacco products

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Additionally, the risk quotient (RQ) values were greater than 1, indicating a potential threat to the water environment