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It is less expensive and results take longer since an outside lab is involved

Some were randomized controlled trials (RCT, double-blinded or no-blinded), some were one-group or two-group intervention studies with Se, without a control group, or controlled with another treatment

These organoids are created through the appropriate combination of cytokines, small molecules, and/or patterning factors, which direct the differentiation of EBs from pluripotent stem cells toward cells and tissues representative of specific brain regions (Zhang et al., 2001

References Bharucha AE, Lacy BE