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Description

Luo H, Shan X, Wu J

For research use only not for human consumption Additional information Research Use Only This product is intended exclusively for in vitro laboratory research

10.7324/JAPS.2012.2404 97

Acknowledgements Research in the Quintana lab is supported by grants NS102807, ES02530, ES029136, AI126880 and AI149699 from the NIH

Some channels belong to the group of the ligand-gated channels, which requires the binding of a ligand to the receptor region to modify their conformation and be opened or closed (145, 146)

In summary, the improved response to irradiation that we observed with the combination of sertraline and RT might be due to enhanced increase in ROS levels and oxidative stress in NSCLC cells, thereby eradicating their continuous proliferation and reducing their self-renewal ability