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81 ECs also respond to hypoxia through metabolic alterations

58 , 99 , 100 PDHC deficiency leads to in adequate removal of pyruvate and lactate, resulting in insufficient energy production

Manna, Pulak R., Zackery C

Abstract Objectives: Global diabetes rates are rising sharply, driving a parallel increase in diabetic kidney disease (DKD) - a key diabetic complication