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Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-B

doi: Emmez H, Yildirim Z, Kale A, Tnge M, Durda E, Brcek A, Uanku LN, Doulu F, Kili N, Baykaner MK (2010) Anti-apoptotic and neuroprotective effects of alpha-lipoic acid on spinal cord ischemiareperfusion injury in rabbits

After adjusting for confounders, aspirin use showed lower odds of mortality OR 0.55 [CI 0.47 - 0.64, p- value 0.00] compared to people without aspirin use

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This suggests that the effects of MG extend beyond binding to GSH and involve the inhibition of GSH resynthesis and enzymes that play key roles in its synthesis, thereby promoting ferroptosis

Increasing growth hormone and IGF-1 levels may carry potential risks, including worsening insulin resistance in some individuals and, theoretically, stimulating the growth of existing cancers