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Methods: We used PET/CT to assess changes in CCR2 binding of intravenously-administered 68 Ga-DOTA-ECL1i in the livers of mice with bile duct ligation (BDL)- and carbon-tetrachloride (CCl 4 )-induced liver fibrosis compared with controls

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Prognosis of gamma-glutamylcysteine synthetase deficiency, gamma-glutamyl transpeptidase deficiency, 5-oxoprolinase deficiency and dipeptidase deficiency is unclear and difficult to predict as very few patients have been reported worldwide

The ratio of 1 h-HepOrg to 25 portal fibroblasts and 100 cholangiocytes better captured the tissue cell ratios at day 6 after assembloid formation and was selected for further experiments (Extended Data Fig