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Excessive Alcohol Consumption: High alcohol intake burdens the liver, where glutathione is concentrated

10.3389/fphar.2023.1264842 [DOI] [PMC free article] [PubMed] [Google Scholar] Brundu S., Palma L., Picceri G

These findings underscore the critical role of ferroptosis in AAA pathogenesis and suggest that targeting GPX4 may represent a promising therapeutic strategy for the clinical management of AAA

Statistical analyses were performed using SAS version 9.4 (SAS Institute Inc.)

Spermidine can reduce the expression of TFR1 and ALOX15, and upregulate Nrf2 and SLC7A11 expression

It activates AMPK the cellular energy sensor that flips the body toward fat-burning and metabolic efficiency