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A comprehensive re-evaluation should include assessment of eating patterns, physical activity levels, psychological factors, and potential anatomical complications before concluding that pharmacotherapy is appropriate

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The mechanisms underlying these effects likely involve glutathione's role in reducing oxidative stress in metabolic tissues, supporting mitochondrial function and energy production, and modulating inflammatory pathways that affect metabolic regulation

doi: 10.1016/j.bcp.2022.115103 50 SrisongkramTBahramiKJrvinenJTimonenJRautioJWeerapreeyakulN

A quick look at the chart indicates a huge separation between the ME/CFS patients (in red) and the healthy controls (in blue)