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Patients with severe mitral regurgitation where mitral surgery is not recommended (for example, patients with very high surgical risk) may be candidates the MitraClip system

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Methods 8, 135138

Homocarnitine is an analogue of carnitine one carbon longer that is synthesised in mammals by hydroxylation of -valerobetaine derived from the microbiome

This mirrors the clinical pigmentation curve, where melanin density climbed over the first 2 weeks before plateauing (Haylett et al., 2011)

This section addresses why this happens and when it matters