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Quickstart Highlights FOXO4-DRI (also known as Proxofim) is a synthetic D-retro-inverso peptide designed to selectively induce apoptosis in senescent cells by disrupting the FOXO4p53 protein interaction [1] [2]

doi: 10.4067/S0718-04622006000200010 79 GarciaEICElghandourMMKhusroAAlcala-CantoYTirado-GonzlezDNBarbabosa-PliegoAet al

Studies on periodontal disease models show the peptide significantly reduced plasma extravasation, histological alterations, and alveolar bone resorption