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While the complex relationship between CFTR dysfunction and oxidative stress, as well as the clinical outcomes of antioxidant therapies, have been discussed at length in numerous excellent reviews (Galli et al., 2012

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This is supported by studies in which humans were exposed to tracer levels of radioiodine as either I 2 or methyl iodide, and in studies in which monkeys inhaled particulate aerosols of sodium iodide (Black and Hounam 1968

These observations suggested that the non-detachable micro-sized cPLT-protein complexes demonstrated poor infiltration within the plaques

As a disulfide bond can be cleaved and hence reduced by the excess concentration of a thiol (sulfhydryl) like -mercaptoethanol (which gets oxidized in the process), the free thiol on glutathione can act as a reducing agent in the cell