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Description

In mice, bile acids can breach the BBB by activating the nuclear receptor farnesoid X receptor (FXR) in the ileum

[5]Seneviratne, Uthpala

These thresholds were chosen to balance biological relevance, statistical significance, and clinical translational feasibility

Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide

PD is characterized by an altered gut microbiota composition, the intestinal barrier, and the enteric neuroimmune system, therefore it is possible that intestinal barrier dysfunction may play a key role in PD development and/or progression