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For example, heparinase, an enzyme that degrades heparan sulphate and enhances the invasive and metastatic capacity of cancer cells, was reported to be activated by s -cysteinylation

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This is important as the lining prevents toxins and bacteria from escaping from the gut

Urology 49 , 644651 (1997)

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The targeted 3-PLG-ibu-A-GSH and ibuprofen at higher, 1.5 M concentration (the estimated drug content of the 3-PLG-ibu-A-GSH nanocarriers) significantly protected against the barrier damaging effect of cytokines with the ibuprofen-coupled targeted nanocarrier group showing the highest effect against BBB dysfunction (Fig