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The domain-swapped dimer, previously observed in crystal structures, is the repeating unit, and helical formation is driven by inter-dimeric RD interactions, i.e., between the RDs of neighbouring subunits of the filament

Results Oxidative stress in FH-deficient cells To elucidate the metabolic changes that occur on the loss of FH, we utilized the previously characterized mouse FH-deficient kidney cells ( Fh1 / ) and their wild-type (wt) isogenic control ( Fh1 fl/fl ) (ref

Carnitine synthesis (lysine and methionine, ascorbic acid, vitamin B6 and niacin)

P = 0.67

Curcuminoids form reactive glucuronides in vitro

That makes it a strong option for laboratories focused on pathway mapping, structured signaling models, and metabolic system analysis with a narrower research lens