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The contribution of oxidative stress to necroptosis appears to be highly context-dependent

In addition, large amounts of the mitochondria-specific phospholipid cardiolipin (CL) were administered by oxidative modification in GPX4 -/- kidneys[33]

7,8 Thus, GOx was recently explored to be co-delivered with Fenton/Fenton-like agents to realize cascade catalysis

Glutathione conjugation is catalyzed by glutathione S-transferase (GST), a family of enzymes that facilitate the binding of glutathione to target molecules

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