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Description

Le flux lysosomal du cholestrol libre (FC) est essentiel la production d'oxystrols qui dclenche l'activation du LXR (Liver X receptor, entranant une augmentation de l'expression du transporteur ABCA1 et de l'efflux de cholestrol pour liminer le cholestrol des cellules (LAL (Lysosomal Acid Lipase) Promotes Reverse Cholesterol Transport In Vitro and In Vivo 2018)