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The polyurea generation 4 (PURE G4 ) dendrimer was already explored as nanocarrier of several drugs by our group in the context of ovarian [26, 27], lung [28], and breast cancer [29] and even in the context of endothelial cells activation and cancer angiogenesis [29]

Our data establish that expanded polyglutamine proteins can concentrate at IFD inclusions, consistent with the idea that IFDs mark and sequester a domain of aggregated proteins, similar to what has been reported for mammalian aggresomes

Both emerged from the same scientific goal make GHRH useful as a therapeutic by overcoming its impractically short duration of action but they took different routes and reached different destinations

Available at: Jung SY et al (2011): Short-acting nifedipine and risk of stroke in elderly hypertensive patients

however, the C-terminal Rhod domain was not visible in these maps (Fig