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2014 (Int J Colorectal Dis) Type Phase II Subjects 117 bowel surgery patients (NCT00672074) Key Finding Ipamorelin 0.03 mg/kg IV twice daily was tolerated similarly to placebo

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Loss of aqp4 polarized localization with loss of beta-dystroglycan immunoreactivity may induce brain edema following intracerebral hemorrhage

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In a recent study, Liskiewicz and colleagues discovered that long-acting GIP receptor agonists activate GABAergic neurons that express the GIP receptor in the area postrema, and that GIP receptor signaling in GABAergic neurons is necessary for the effects of GIP to lower body weight [151]