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1 pump = 50 mg For children 2-11 use 1/2 to 1 pump

doi: 10.3389/fnut.2024.1406147 Received 24 March 2024 Accepted 17 July 2024 Published 09 August 2024 Volume 11 - 2024 Edited by Sladjana Sobajic, University of Belgrade, Serbia Reviewed by Mina Ahmadzadeh, Shahid Beheshti University of Medical Sciences, Iran Hongye Peng, China Academy of Chinese Medical Sciences, China Updates Copyright 2024 Zhuang, Li, Wu, Zhang, Zhang and Dong

It has been shown that ROS builds up in the gastric carcinoma cells after exposure to 5-FU activates HIF-1-(HMGB1) signaling, which recruits M2 TAMs, which generates GDF15 (growth differentiation factor 15), and enhances fatty acid -oxidation thus increasing the chemoresistance in them [278]

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CSC markers have been reported to promote multi-drug resistance by modulating drug efflux pumps