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doi:10.1016/j.forsciint.2018.09.030

If your doctor or health care provider is just rapid firing it in (which is always more painful), hitting the bone, you have Botox running down your face, it is more painful than when you get it done with other providers, or you get eye-lid droopiness (ptosis), you should think about moving on to someone with a more refined technique

Pontzer H, Yamada Y, Sagayama H, Ainslie PN, Andersen LF, Anderson LJ, Arab L, Baddou I, Bedu-Addo K, Blaak EE, et al

A 150-pound and a 250-pound patient typically use similar doses because the mechanism is signaling-based rather than concentration-based

Supplementary Figure S4B)

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