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Description

Clinical cohort studies confirm that cerebrospinal fluid levels of lipid peroxidation markers (e.g., MDA, 8-OHdG) are significantly elevated in APOE4 carriers compared to APOE2 carriers, exhibiting a strong positive correlation with the rate of hippocampal atrophy (199)

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doi: 10.1038/sj.ijo.0803695

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Paraneoplastic Syndromes

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We found that in mammalian brain, the absence of endogenous parkin is compensated by the following redox indices: an elevation in GSH concentrations

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