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Journal of Thoracic Disease 15(10):5507-5516, 2023

Gibbons, pers

doi: 10.1007/s12016-021-08848-3

Lean ME, Leslie WS, Barnes AC, Brosnahan N, Thom G, McCombie L, et al

Simultaneously, studies using molecular biology detection and pharmacological intervention confirmed that heat stress triggers cPLA2 activation and increases the level of its metabolite arachidonic acid to participate in lipid peroxidation in the mouse heatstroke model, further promoting the occurrence of ferroptosis, thereby aggravating the progression of ALI after heat stress [48]