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Thus, in an experimental model of DOX-induced POI in adult female albino rats, this research seeks to assess the possible consequences of SP and/or L-car on the prevention of primordial follicular reserve depletion, preservation of ovarian follicular structure and function, and improvement of long-term post-chemotherapy fertility utilizing immunohistochemistry, histology, biochemistry, and molecular studies

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4 Heavy Drinking NIAAA defines heavy drinking as follows: For men, consuming five or more drinks on any day or 15 or more per week For women, consuming four or more on any day or eight or more drinks per week SAMHSA defines heavy alcohol use as binge drinking on five or more days in the past month