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This differential role depends on their ability to confer different properties to adrenergic 2A receptor ( 2A R)-D 4 R heteromers and dopamine D 2 receptor (D 2 R)-D 4 R heteromers, preferentially localized in the perisomatic region of the frontal cortical pyramidal neuron and its striatal terminals, respectively

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Using these guidelines, we have shown that compounds previously identified as eryptosis inducers failed to induce eryptosis of nave and P

doi: 10.3389/fphar.2025.1737199 Received 01 November 2025 Revised 21 December 2025 Accepted 29 December 2025 Published 15 January 2026 Volume 16 - 2025 Edited by Dawei Chen, University of Kiel, Germany Reviewed by Eveljn Scarian, University of Pavia, Italy Hong Cheng, Yangzhou University, China Updates Copyright 2026 Knudsen, Tadje, Coggins and Venketaraman