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Scientific Communications: pathophysiology 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.01 - ACUTE MANAGEMENT - Neither thrombolysis nor thrombectomy O - ESOC25-1367 EFFECT OF CEREBROLYSIN ON CIRCULATING TIGHT JUNCTION PROTEINS AFTER REPERFUSION THERAPY Sawomir Michalak 1 , Jacek Namysl 2 , Krystyna Osztynowicz 3 , Joanna Rybacka-Mossakowska 2 1 Poznan University of Medical Sciences, Department of Neurochemistry and Neuropathology, Stroke Unit University Hospital Poznan, Poznan, Poland, 2 Poznan University of Medical Sciences, Stroke Unit University Hospital Poznan, Poznan, Poland, 3 Poznan University of Medical Sciences, Poznan, Poland Background and Aims: Experimental studies revealed that Cerebrolysin affects the integrity of the blood-brain barrier (BBB)

Treatment Length: Typical protocols run 812 weeks , depending on symptom severity and treatment goals

Analyzing the Amino Acid Composition The amino acid composition (UNIT 3.2) of the protein will also allow calculation of some basic physicochemical parameters

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However, most of the investigations in this area are limited to experimental studies and, therefore, further investigations should examine this effect of riboflavin through observational and interventional studies in human populations

By exploring the mechanisms behind their therapeutic effects, we aim to illuminate the potential of natural compounds as complementary or alternative approaches for managing this challenging condition