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FIGURE 2 Epigenetic modifications in key genes related to stress and immunity, such as nuclear receptor subfamily three group C member 1 (NR3C1), TNF, and nuclear factor kappa B (NF-B), modulate both the negative feedback of the HPA axis and inflammatory pathways mediated by NF-B, suggesting a link between endocrine dysregulation and immune activation (Palma-Gudiel et al., 2021)

doi: 10.1016/j.arr.2023.102077 64

Nrf2is a key factor in the control of the expression of genes involved in the regulation of oxidative stress, via the enhanced production of cellular antioxidants

Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response

Glucose Homeostasis: Studying the modulation of insulin sensitivity and carbohydrate metabolism

In refractory cases that have not responded to conservative management or nerve blocks, surgical decompression of the lateral femoral cutaneous nerve may be considered as a last resort