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Our analysis reveals critical molecular pathways, including NF-B and JNK signaling, that fundamentally compromise metabolic function

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2.4 Determination of Gastric Ulcer Index The stomachs from different groups were opened along their greater curvature, cleaned with cold normal saline, blotted between two filter papers to dry them, and placed on a cardboard for gross examination of ulcers

NEJM Evid 2025;4:EVIDoa2400243

Methods: To investigate the roles of GSTM1 and GSTT1 in cisplatin-induced AKI, we generated GSTM1 and GSTT1 knockout mice using CRISPR-Cas9 technology and assessed their kidney function under normal physiological conditions and cisplatin treatment

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