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It is possible that -karyopherins and Ran-GTP coevolved under selective pressure to achieve efficient and rapid nuclear import

Molecular Medicine 1997, 3: 617-627

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A trienone analog of curcumin, 1, 7-bis (3-hydroxyphenyl)-1, 4, 6-heptatrien-3-one, possesses ROS-and caspase-mediated apoptosis in human oral squamous cell carcinoma cells in vitro

A copper chelate selectively triggers apoptosis in myeloid-derived suppressor cells in a drug-resistant tumor model and enhances antitumor immune response