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h , Dot plot visualization of gene expression for Type I (asymmetric dimethyl-) PRMTs (PRMT2, PRMT3, PRMT6, and PRMT8), Type II (symmetric dimethyl-) PRMTs (PRMT5 and PRMT9), and Type III (monomethyl) PRMT (PRMT7)

Methods: We developed a biomimetic autophagy degradation peptide (MNP-PDL1) using the lysosomal autophagy system in conjunction with biomimetic membrane technology, which consists of a PD-L1-binding sequence, a PEG3 linker, and a target lysosomal chaperone protein recognition sequence (CIP), which can localize the target protein, PD-L1, to the lysosome for degradation

Additionally, T1D induced changes in intestinal health and function have been suggested to contribute to further T1D complications, such as osteoporosis [166]

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