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the topical administration provides the benfotiamine and pyridoxamine-containing formulation directly to the skin, which is preferably provided with the use of a dermatologically acceptable carrier

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248 Due to the stable covalent interaction the problem of effective release of the drug payload on the target site needs to be addressed

Danielle Blundell is a New Jersey-based lifestyle writer and editor who has written on topics ranging from home and health to beauty for a variety of publications, including Rachael Ray Every Day, Redbook, Family Circle , This Old House , Elle Decor , Esquire , Domino, and Apartment Therapy