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DOI: 10.2337/dc10-1006

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Numerous cell cycle regulating systems are usually impaired in cancerous cells, which is frequently observed in the phenotype of the malignant tumour cells (64)

Moreover, berberine also reduces the expression of PD-L1 on the surface of tumor cells, interfering with the mechanism by which tumor cells use the PD-1/PD-L1 pathway to evade the immune system

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J., Kroll, D