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SKU: 98056513491
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These resistance mechanisms are not isolated

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doi: 10.1292/jvms.65.237 53

Misawa K, Hasegawa T, Mishima E et al (2020) Contribution of rare variants of the SLC22A12 gene to the missing heritability of serum urate levels

Preclinical evidence Mice with a deletion of the 22q11.2 locus containing most proteins expressed in mitochondria [19] show increased cytoplasmic 8-oxo-2-deoxyguanosine (suggesting mitochondrial DNA oxidation), reduced number of PV-immunoreactive interneurons, and weakened PNN in anterior cingulate cortex [15]