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Since hormonal fluctuations in females can introduce additional variability, male mice were selected to improve the reproducibility and consistency of the data across the multi-omics analyses performed

In this section twelve mice were divided into four groups (0d, 1d, 3d and 7d) with 3 mice in each group

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All data were analyzed using SPSS version 20.0 (IBM Corp., Armonk, NY, USA)

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