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This augmented height can lead to the production of pro-inflammatory cytokines such as IFN-, which promotes B cell class switching and initiates pathogenic autoantibodies production such as Immunoglobulin G (IgG) antibodies, most notably anti-dsDNA antibodies, typical lupus-characteristic markers, that induce additional inflammation and tissue damage (115, 118)

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Table (1): Functional group of the crude extract of Burkholderia stagnalis Table (2): Bioactive compounds of the crude extract of Burkholderia stagnalis Molecular profiling Molecular profiling, combined with sequence alignment using the NCBI BLAST database, revealed that the bacterium exhibited similarity to Burkholderia stagnalis

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