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These findings might be relevant for patients carrying mutations in FA-detoxification systems and could suggest therapeutic benefits from thiol-rich antioxidants like N-acetyl-L-cysteine

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These changes subsequently inhibit ferroptosis in ovarian granulosa cells, ultimately improving IR and ovarian function, which contributes to its therapeutic efficacy in PCOS ( 5.1.3 Polysaccharide Astragalus polysaccharide (APS) is a water-soluble heteropolysaccharide extracted from the stems or dried roots of Astragalus membranaceus and represents the most abundant and biologically important component of this herb

During seed germination, a delayed degradation of PSVs was also observed in the snx1 mutant and the snx1/snx2a/snx2b triple mutant (Fig

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This research was supported by the Ovarian Cancer Research Alliance (CRDG-2022-889057 to J-T.C.), the U.S