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The gastrointestinal tract is one of the most underestimated research environments in preclinical science

Annu Rev Biochem 52:711760 Meister A, Tate SS (1976) Glutathione and related gamma-glutamyl compounds: biosynthesis and utilization

HCAEC, human coronary artery endothelial cells

Of note, Tempol is cell-permeable and not compartment-specific and hence reduces O 2 levels everywhere in the cell [373,374]

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