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So even though they are no longer formally restricted by Category 2, the affirmative basis to compound them at scale still doesnt exist

FIGURE 9 Discussion Nrf2 is a key member of cap-n-collar basic leucine zipper transcription factor family, and is also a key regulator of mammalian genes involved in cell protection and detoxification by preventing oxidative stress ( As the first step of metabolism, the liver is often exposed to high concentrations of exogenous and endogenous metabolites, especially vulnerable to oxidative damage caused by intermediate active substances

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