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FIGURE 5 Since this enzyme participates in the cytosolic maintenance of NADPH levels (Yin et al., 2012), we also evaluated mitochondrial enzymes activities linked to NADP + reduction

In addition, SH-SY5Y cells treated with GHK exhibited significant increases in cell viability as well as decreases in the level of LDH release caused by hemin-induced injury

The encapsulation of the GDNF by the NPs protects them from being degraded from enzymatic attack and facilitates delivery to the brain

This may lead to a better accessibility to the ubiquitination machinery (Supplementary Fig

To demonstrate specificity of the effect, we sought to rescue the decreased mEPSC frequency by pretreating with pyroglutamate (PGA), the precursor of glutamate that is synthesized downstream of GGT, which is blocked by acivicin (Fig

The iron redox and hydrolysis chemistry of the ferritins