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Invading white blood cells secrete pro-inflammatory factors, which trigger reactive response of neural parenchymal cells, most notably reactive astrogliosis and microgliosis

Additionally, lipophagy, the degradation of lipid droplets, results in increased lipid release, leading to lipid peroxidation and ferroptosis [132]

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We believe that the three-dimensional structure of the hTrxR1hTrx1 complex will facilitate future drug discovery approaches and will significantly contribute to our understanding of redox regulatory processes in mammals

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