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Primary Cellular Pathways Nicotinic Acetylcholine Receptor Antagonism Neuromuscular Blockade The primary mechanism of Syn-AKE involves binding to the epsilon subunit of muscular nicotinic acetylcholine receptors (mnAChR), preventing acetylcholine from binding and initiating muscle contraction[1]

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Generally well-tolerated with minimal reports of mild headaches or nasal irritation

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