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10.1016/j.jbiosc.2016.03.015 289 ZhuZ.-Y.LiuN.SiC.-L.LiuY.DingL.-N.JingC.et al (2012a)

doi:10.1016/j.ecl.2020.10.004 Kulkarni AD, Jamieson DJ, Jones HW, Jr., et al

Supplementary material The Supplementary Material for this article can be found online at: Abbreviations BCA, bicinchoninic acid

En otro estudio, la energa "ahorrada" al reemplazar la sacarosa con edulcorantes no nutritivos (NNS) en bebidas edulcoradas fue totalmente compensada en las comidas subsiguientes

Important safety considerations include the risk of hypersensitivity reactions and the need for renal function monitoring during treatment

Similarly, another study demonstrated no difference in the VPT between the treatment and placebo groups.(11) Only one study demonstrated statistically significant (p = 0.006) improvement in the nerve conduction velocity of the peroneal nerve by 1.1 m/s compared to that of the placebo group, which dropped by 2.7 m/s.(13) This same study also showed a statistically upward trend in the VPT, approaching a mean of 1.4 m at week 12 of treatment compared to 2.0 m at baseline.(13) Of the three studies that looked at neuropathic symptoms as a primary outcome measure, only one showed improvement in this aspect