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Contributing factors involve hepatic de novo synthesis of cholesterol, reverse cholesterol transport generating HDL cholesterol [25], and hepatic uptake of intestinal chylomicrons

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PI-IBS is diagnosed when at least 6 months have passed since the initial infection and symptoms have been present for at least 3 months

The inhibition of the NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome pathway by formononetin may be the reason for this effect (de Camargo et al., 2019)